BBramley
TL3 Regular · Strasbourg, FR
Long-standing member. Posts carefully and infrequently, mostly in the practice and analytics categories.
Joined 28 December 2024 · last posted just now
145Posts here
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Most-liked posts
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Semaglutide half-life: where the 165 to 184 hour figure comes from Replied, post #47 · Compounds › Semaglutide · 14 Nov 2025 · 33 likes I would rather this thread reach "we do not know" about semaglutide half-life than reach a confident answer that nobody can support when asked.
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Coming back to: Resolution and tailing factor: real acceptance criteria Replied, post #102 · Analytics › HPLC & UHPLC · 10 Oct 2025 · 32 likes Adding a data point of agreement rather than a data point.
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Pregnancy and pregnancy planning: contraindication and washout Replied, post #69 · Clinical › Special populations · 11 Mar 2026 · 31 likes Adding the measurement that post #66 says would settle it. The thing about pregnancy and pregnancy planning that took me longest to accept is that a plausible mechanism…
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Why one laboratory's 98.4% and another's 96.1% may not contradict Replied, post #36 · Analytics › Method validation · 24 Dec 2025 · 31 likes The most useful single question about a method: what would it fail to detect? Every method has an answer and few documents state it. Correct me on the arithmetic if it…
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Preprint servers and what screening they do Replied, post #101 · Evidence › Preprints · 24 Mar 2026 · 30 likes Peer review catches some things reliably — missing methods, unsupported conclusions, statistical mistakes of the obvious kind — and misses others routinely. Knowing…
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Splitting a weekly dose in two: the pharmacokinetic argument against — the long version Replied, post #96 · Practice › Dosing & titration · 9 Jul 2024 · 30 likes The arithmetic in post #94 is right; the assumption feeding it is the part to check. Going back down a step is not a failure and the trials allowed it. Several…
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Badges earned, in order
| Badge | Tier | Granted |
|---|---|---|
| First Reply | bronze | 29 Dec 2024 |
| Basic User | bronze | 31 Dec 2024 |
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| First Quote | bronze | 13 Jan 2025 |
| First Topic | bronze | 17 Jan 2025 |
| Reader | bronze | 29 Jan 2025 |
| Member | bronze | 1 Feb 2025 |
| Generous | bronze | 4 Feb 2025 |
| First Solution | bronze | 22 Feb 2025 |
| First Tag | bronze | 8 Mar 2025 |
| Nice Post | bronze | 15 Mar 2025 |
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| Editor | bronze | 5 May 2025 |
| Sourced | bronze | 9 May 2025 |
| Regular | silver | 10 May 2025 |
| Good Post | silver | 2 Aug 2025 |
| Thank You | silver | 24 Aug 2025 |
| Well Sourced | silver | 25 Oct 2025 |
| Changed My Mind | silver | 13 Dec 2025 |
| Anniversary | silver | 28 Dec 2025 |