f.laurent
TL2 · Graz
Contributes reviews on supplier material. Based in Graz.
Joined 28 September 2024 · last posted 3d
73Posts here
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Second pass at: A pooled estimate that changed when one trial was added Started this topic · Evidence › Meta-analyses · 5 May 2026 · 39 likes On the subject in the title: Second pass at: A pooled estimate that changed when one trial was added Working notes rather than a conclusion. Two things I would like…
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[2026 update] An appeal that failed, and what I would do differently Replied, post #10 · Access › Insurance & coverage · 6 Jun 2025 · 33 likes Formulary status: the list of covered medications and the tier (how much you pay) they are on. Checking the current formulary before going to a clinic appointment saves…
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Journal club: SURMOUNT-1, read without the press release Replied, post #55 · Evidence › Journal club · 4 Feb 2025 · 32 likes Taking post #54 at face value and following it one step further. A methods point on SURMOUNT-1 rather than a substantive one: if the comparison is not like for like,…
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[2026 update] What we do not know about retatrutide, listed explicitly Replied, post #8 · Compounds › Retatrutide · 11 Jul 2025 · 31 likes Worth separating two things that post #6 runs together. Heart rate increased in a dose-dependent way in the phase 2 work. That is not a footnote — it is one of the…
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Biased agonism: a real phenomenon, an over-used explanation Replied, post #95 · Pharmacology › Receptor biology · 14 Mar 2025 · 31 likes Biased agonism — where different ligands at the same receptor favour different downstream pathways — is a plausible explanation for differences between compounds in…
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Vomiting: when it is expected and when it is a reason to stop — one year on Replied, post #10 · Practice › Side effects · 23 May 2026 · 29 likes The published rates come from populations that were titrated on a defined schedule with clinical supervision. Rates from a forum are not comparable and are biased by…
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Badges earned, in order
| Badge | Tier | Granted |
|---|---|---|
| First Reply | bronze | 29 Sep 2024 |
| Basic User | bronze | 2 Oct 2024 |
| Read the Guidelines | bronze | 4 Oct 2024 |
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| First Solution | bronze | 16 Jan 2025 |
| Nice Post | bronze | 12 Mar 2025 |
| Good Post | silver | 14 Mar 2025 |
| Nice Topic | bronze | 18 Apr 2025 |
| Good Topic | silver | 24 Apr 2025 |
| Anniversary | silver | 28 Sep 2025 |