p.krastev
TL2 · Lyon
Contributes reviews on supplier material. Based in Lyon.
Joined 6 April 2025 · last posted 8d
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Reading a supplementary appendix and finding the interesting part Started this topic · Evidence › Trials · 29 Sep 2024 · 52 likes Reading a supplementary appendix and finding the interesting part — setting out what I have, and where I think it stops being reliable. Collecting what is known about…
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A 5 mg vial and a 0.25 mg dose: the arithmetic in full — the long version Replied, post #144 · Practice › Reconstitution · 24 Jun 2025 · 33 likes Arithmetic step by step: a 5 mg vial with 2 mL of diluent gives (5 mg) / (2 mL) = 2.5 mg/mL. On a U-100 syringe at that concentration, 100 units = 1 mL = 2.5 mg, so…
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Time to steady state after a dose increase Replied, post #136 · Pharmacology › Pharmacokinetics · 6 Nov 2024 · 33 likes I had written a reply contradicting post #134 and deleted it. Here is what survived. The time to maximum concentration after a subcutaneous dose in this class is…
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Coming back to: Lateral-flow and colorimetric approaches: the specificity problem Replied, post #29 · Analytics › Home & field testing · 24 May 2026 · 32 likes Building on post #28 rather than restating it. An update on my earlier Lateral-flow and colorimetric approaches post: the pattern held for another six weeks and then…
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Adjudicated events and why the definition matters — the long version Replied, post #120 · Evidence › Trials · 26 Apr 2025 · 32 likes Risk of bias: structured appraisal of internal validity. Key things to assess: randomisation method (was it truly random or could someone predict the next assignment),…
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A promotion I argued against, and why I lost Replied, post #110 · Documentation › Doc review · 24 Feb 2025 · 32 likes This follows post #109 rather than contradicting it. Worth stating the null on promotion before we explain it: the observation may be nothing. That possibility deserves…
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