20 categories

Clinical

Laboratory interpretation, comorbidities, special populations, and preparing for a conversation with your own prescriber. General information only.

96 topics4,480 posts30 solved Moderators: bench_notes, hana.sato About this category

Bloodwork 30 Comorbidities 24 Special populations 22 Prescriber conversations 20

96 topics · page 3 of 4

Topic	Participants	Replies	Views	Activity
Asking about a compound your prescriber has not heard of Clinical › Prescriber conversations telehealth prior authorisation beginner friendly Asking about a compound your prescriber has not heard of Writing it up because I had to work it out twice and would rather nobody else did. A question about how to describe something to a clinician rather…	+137	148	15k	11mo
[2026 update] Cardiovascular risk: reading the outcome trials as a set Clinical › Comorbidities PCOS type 2 diabetes chronic kidney disease blood pressure Posting this under the heading it deserves: Cardiovascular risk: reading the outcome trials as a set Everything below is what sits behind that. I have spent a fortnight trying to pin Cardiovascular risk down…	+99	103	32k	11mo
Preparing for an appointment: one page, three questions Clinical › Prescriber conversations prior authorisation type 2 diabetes telehealth Posting this under the heading it deserves: Preparing for an appointment: one page, three questions Everything below is what sits behind that. A question about how to describe something to a clinician rather…	+28	32	57k	11mo
Older adults, sarcopenia risk, and the trade-off nobody quantifies — does this still hold? Clinical › Special populations disordered eating chronic kidney disease pregnancy & planning Solved Asking directly, because I could not find a straight answer: Older adults, sarcopenia risk, and the trade-off nobody quantifies — does this still hold? Older adults: setting out the arithmetic in full,…		2	22k	11mo
Biological variation versus analytical imprecision Clinical › Bloodwork lipase & amylase liver enzymes thyroid function HbA1c On the subject in the title: Biological variation versus analytical imprecision Working notes rather than a conclusion. A question about biological variation versus analytical imprecision that I think has a…		2	42k	12mo
Discussing something you have already been doing — the long version Clinical › Prescriber conversations telehealth prior authorisation beginner friendly type 2 diabetes Solved Discussing something you have already been doing — the long version Writing it up because I had to work it out twice and would rather nobody else did. A question about how to describe something to a clinician…	+14	18	58k	12mo
Hepatic steatosis: what the MASH trial evidence supports Clinical › Comorbidities MASH / hepatic steatosis PCOS type 2 diabetes chronic kidney disease Hepatic steatosis: what the MASH trial evidence supports — setting out what I have, and where I think it stops being reliable. Trying to work out what would count as evidence on hepatic steatosis, before…	+77	83	950	13mo
Obstructive sleep apnoea and a hard endpoint in this class Clinical › Comorbidities chronic kidney disease PCOS obstructive sleep apnoea blood pressure On the subject in the title: Obstructive sleep apnoea and a hard endpoint in this class Working notes rather than a conclusion. I was wrong about obstructive sleep apnoea in a thread last spring and I would…	+120	129	1.8k	13mo
[2026 update] Gastro-oesophageal reflux: improving or worsening? Clinical › Comorbidities chronic kidney disease MASH / hepatic steatosis PCOS blood pressure Solved Asking directly, because I could not find a straight answer: Gastro-oesophageal reflux: improving or worsening? Gastro-oesophageal reflux — I have the observation and I do not trust my interpretation of it,…		3	782	13mo
Lipase elevation without symptoms: the interpretation problem — a second dataset Clinical › Bloodwork lipid panel liver enzymes HbA1c eGFR & renal function Wiki Closed Posting this under the heading it deserves: Lipase elevation without symptoms: the interpretation problem — a second dataset Everything below is what sits behind that. Posting a small dataset on Lipase…	+6	15	2.2k	13mo
Coming back to: Getting a referral rather than a refusal Clinical › Prescriber conversations prior authorisation telehealth type 2 diabetes beginner friendly Solved Posting this under the heading it deserves: Getting a referral rather than a refusal Everything below is what sits behind that. Working notes on Getting a referral rather than a conclusion. I would rather…	+69	74	1.7k	13mo
How to bring a laboratory report to an appointment usefully Clinical › Bloodwork thyroid function lipase & amylase lipid panel eGFR & renal function How to bring a laboratory report to an appointment usefully — that is the question, and I have not found it answered plainly anywhere I have looked. Asking about bring a laboratory directly, because I have…		2	41k	14mo
[2026 update] Building a sensible monitoring schedule with your prescriber Clinical › Bloodwork thyroid function HbA1c lipid panel lipase & amylase Closed Posting this under the heading it deserves: Building a sensible monitoring schedule with your prescriber Everything below is what sits behind that. Reading back through what has been written here about…	+22	26	5.1k	14mo
HbA1c lag and what it can and cannot tell you at eight weeks Clinical › Bloodwork HbA1c lipid panel thyroid function lipase & amylase Solved HbA1c lag and what it can and cannot tell you at eight weeks Writing it up because I had to work it out twice and would rather nobody else did. Something about hba1c lag does not reconcile and I would like a…	+14	18	2.6k	14mo
Second pass at: Obstructive sleep apnoea and a hard endpoint in this class Clinical › Comorbidities type 2 diabetes obstructive sleep apnoea MASH / hepatic steatosis chronic kidney disease Second pass at: Obstructive sleep apnoea and a hard endpoint in this class — setting out what I have, and where I think it stops being reliable. Something about Obstructive sleep apnoea does not reconcile and…		2	726	14mo
Micronutrient status when intake falls substantially — a second dataset Clinical › Bloodwork thyroid function eGFR & renal function lipid panel lipase & amylase Closed Micronutrient status when intake falls substantially — a second dataset Writing it up because I had to work it out twice and would rather nobody else did. Posting a small dataset on Micronutrient status. It…	+9	13	274	14mo
Second pass at: A single out-of-range value on an otherwise normal panel Clinical › Bloodwork thyroid function lipid panel eGFR & renal function lipase & amylase Second pass at: A single out-of-range value on an otherwise normal panel Writing it up because I had to work it out twice and would rather nobody else did. General question, not a request for advice about my…	+9	13	8.5k	16mo
Revisiting: Heart failure with preserved ejection fraction: symptom endpoints Clinical › Comorbidities chronic kidney disease blood pressure obstructive sleep apnoea On the subject in the title: Revisiting: Heart failure with preserved ejection fraction: symptom endpoints Working notes rather than a conclusion. Working notes on Heart failure with preserved ejection rather…	+4	8	43k	17mo
[2026 update] Lipid changes during rapid weight loss: the expected trajectory Clinical › Bloodwork thyroid function eGFR & renal function lipid panel lipase & amylase Lipid changes during rapid weight loss: the expected trajectory Writing it up because I had to work it out twice and would rather nobody else did. Lipid changes during rapid weight keeps being re-asked here…	+51	56	7.1k	17mo
Coming back to: Renal impairment: what the labelling says about dose Clinical › Special populations chronic kidney disease adolescents disordered eating pregnancy & planning Renal impairment: what the labelling says about dose — setting out what I have, and where I think it stops being reliable. Renal impairment — I have the observation and I do not trust my interpretation of it,…	+30	34	48k	18mo
Gallbladder disease risk with rapid weight loss Clinical › Comorbidities obstructive sleep apnoea type 2 diabetes chronic kidney disease Solved Posting this under the heading it deserves: Gallbladder disease risk with rapid weight loss Everything below is what sits behind that. Gallbladder disease risk — I have the observation and I do not trust my…	+56	63	34k	18mo
Coming back to: Preparing for an appointment: one page, three questions Clinical › Prescriber conversations prior authorisation type 2 diabetes telehealth Posting this under the heading it deserves: Preparing for an appointment: one page, three questions Everything below is what sits behind that. A question about how to describe something to a clinician rather…	+139	151	47k	18mo
Renal impairment: what the labelling says about dose Clinical › Special populations disordered eating adolescents bariatric surgery history older adults Wiki On the subject in the title: Renal impairment: what the labelling says about dose Working notes rather than a conclusion. A methods question rather than a substantive one, about renal impairment. Everyone…		4	8.9k	19mo
People with a low starting BMI: where the evidence stops Clinical › Special populations pregnancy & planning chronic kidney disease older adults Posting this under the heading it deserves: People with a low starting BMI: where the evidence stops Everything below is what sits behind that. Asking about a population rather than about a person. The…	+23	27	5.8k	19mo
Building a sensible monitoring schedule with your prescriber Clinical › Bloodwork HbA1c eGFR & renal function lipase & amylase lipid panel Building a sensible monitoring schedule with your prescriber — setting out what I have, and where I think it stops being reliable. Building a sensible monitoring schedule — I have the observation and I do not…	+91	108	52k	19mo
Second opinions: how to seek one without burning the first Clinical › Prescriber conversations telehealth prior authorisation beginner friendly type 2 diabetes Closed Second opinions: how to seek one without burning the first Writing it up because I had to work it out twice and would rather nobody else did. The question about second opinions that I actually want answered…	+1	5	33k	19mo
Asking about a compound your prescriber has not heard of — one year on Clinical › Prescriber conversations beginner friendly type 2 diabetes prior authorisation Solved Under review On the subject in the title: Asking about a compound your prescriber has not heard of — one year on Working notes rather than a conclusion. A question about how to describe something to a clinician rather…	+11	15	3.7k	19mo
Type 1 diabetes: off-label use and the evidence gap — what changed since Clinical › Special populations adolescents disordered eating older adults Solved Type 1 diabetes: off-label use and the evidence gap — what changed since — setting out what I have, and where I think it stops being reliable. What changes if the standard account of Type 1 diabetes is wrong?…	+68	77	31k	20mo
How to ask for a dose change without antagonising anyone — what changed since Clinical › Prescriber conversations prior authorisation telehealth type 2 diabetes Solved How to ask for a dose change without antagonising anyone — what changed since — that is the question, and I have not found it answered plainly anywhere I have looked. A question about how to describe…	+81	92	10k	20mo
Chronic kidney disease and the FLOW result — a second dataset Clinical › Comorbidities MASH / hepatic steatosis blood pressure type 2 diabetes Chronic kidney disease and the FLOW result — a second dataset Writing it up because I had to work it out twice and would rather nobody else did. Posting a small dataset on Chronic kidney disease. It is mine,…		2	2.3k	20mo