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TL2 · Rosario

Contributes reviews on supplier material. Based in Rosario.

Joined 3 October 2024 · last posted 7d

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Forced degradation studies: designing one that is informative Replied, post #103 · Analytics › Method validation · 21 Jul 2026 · 1 like On forced degradation studies: the maintained page in the documentation commons covers the general case with citations and a review date, which is more reliable than…
A structured critique template this community uses — a second dataset Replied, post #42 · Evidence › Study critique · 18 Jul 2026 · 11 likes Answering the question post #40 raises rather than the one it answers. The strongest critiques cite the section they rely on. A critique without a page reference is an…
What consumer-accessible tests can and cannot determine — a second dataset Replied, post #60 · Analytics › Home & field testing · 7 Jul 2026 · 31 likes Where I part company with post #57, and it is a narrow parting. A home refractometer is not measuring what people hope it is measuring in these preparations, and the…
Micro-titration: a disputed topic, argued properly — one year on Replied, post #58 · Practice › Dosing & titration · 3 Jul 2026 · 12 likes Useful. I had the fact and not the reason, which turns out to be the important half.
Angle of injection and whether 90 degrees is always right — the long version Replied, post #35 · Practice › Administration · 30 Jun 2026 · 5 likes I will take the caveat as seriously as the claim, which is the point of putting it there.
Secretagogues and glucose tolerance: the mechanistic concern Replied, post #55 · Compounds › Secretagogues & GH axis · 30 Jun 2026 · 23 likes Post #52 and I disagree about the size of the effect, not about the direction. The useful distinction on secretagogues and glucose tolerance is between what was…
Specificity, linearity, accuracy, precision, range, robustness — with real criteria Replied, post #36 · Analytics › Method validation · 28 Jun 2026 · 0 likes Linearity across the working range is a routine demonstration and it constrains how far a result can be extrapolated. A method linear from 80 to 120 per cent of nominal…
Publication patterns in the BPC-157 literature, examined Replied, post #23 · Compounds › Repair & healing peptides · 28 Jun 2026 · 20 likes The bit of publication patterns that nobody enjoys is that the answer changes depending on what you are trying to decide with it. Say what the decision is and the…
Manufacturer assistance programmes and their eligibility rules Replied, post #37 · Access › Pricing · 26 Jun 2026 · 14 likes Answering the question post #33 raises rather than the one it answers. The cost of an independent submission is worth stating in these threads, because it is the main…
Revisiting: Theoretical plates: useful number or ritual? Replied, post #12 · Analytics › HPLC & UHPLC · 9 Jun 2026 · 0 likes Post #11 answers the question as asked. The question underneath it is different. The most useful reply I ever got about Theoretical plates was a request to state my…
Racemisation and why it is invisible to a mass measurement Replied, post #23 · Analytics › Impurities & related substances · 9 Jun 2026 · 0 likes Narrowing post #22, because the general version has more than one answer. Dimer and higher-order multimers: two or more peptide molecules bonded together. They appear…
An 18-month record including the parts that went badly Replied, post #28 · Outcomes › Progress reports · 30 May 2026 · 27 likes Rate of change matters more than the absolute number for most of the questions people ask about their own series. I have seen it go both ways, which is why I hedge.