Ranked by engagement

Top topics — all time page 38

Ranked by replies, likes and views over all time, with a bonus for topics that reached a marked solution. Engagement is a proxy for usefulness and a poor one; the documentation commons is the better index of what is settled.

This week This month This quarter This year All time

1,535 topics · page 38 of 40

Topic	Participants	Replies	Views	Activity
Turnaround times and what they mean for a decision Sourcing › Independent verification PeptideMeter Medutest Janoshik Analytical VendorInvestigate Turnaround times and what they mean for a decision Writing it up because I had to work it out twice and would rather nobody else did. A question about turnaround times that I think has a definite answer,…		4	29k	3mo
Risk-of-bias tools and the judgement they conceal Evidence › Meta-analyses meta-analysis heterogeneity publication bias effect size Wiki Risk-of-bias tools and the judgement they conceal Writing it up because I had to work it out twice and would rather nobody else did. I have spent a fortnight trying to pin risk-of-bias tools down and I want…	+8	12	21k	11mo
When a tidy document is a signal and when it is decoration — does this still hold? Analytics › COA interpretation reference standards amino acid analysis documentation quality certificate of analysis Solved Asking directly, because I could not find a straight answer: When a tidy document is a signal and when it is decoration — does this still hold? Tidy document keeps being re-asked here and I think that is…	+3	7	22k	11mo
Open-label extensions: what survives and what does not Evidence › Trials discontinuation & dropout randomised trial estimand Closed Posting this under the heading it deserves: Open-label extensions: what survives and what does not Everything below is what sits behind that. I have spent a fortnight trying to pin open-label extensions down…		4	22k	3mo
Follow-up: Lyophilisation and why the cake looks the way it does Pharmacology › Formulation chemistry bacteriostatic water cloudy or discoloured solution sterile water Solved Lyophilisation and why the cake looks the way it does Writing it up because I had to work it out twice and would rather nobody else did. I was wrong about Lyophilisation in a thread last spring and I would…	+10	14	11k	3mo
Reading a denial letter as a specification for your appeal Access › Insurance & coverage appeals prior authorisation insurance Closed Reading a denial letter as a specification for your appeal Writing it up because I had to work it out twice and would rather nobody else did. Reading back through what has been written here about reading a…		3	30k	12mo
Deletion sequences: expected mass shifts by residue — the long version Analytics › Impurities & related substances water content endotoxin testing data table forced degradation On the subject in the title: Deletion sequences: expected mass shifts by residue — the long version Working notes rather than a conclusion. Deletion sequences keeps being re-asked here and I think that is…	+21	25	6.9k	10h
About the Mass spectrometry category Analytics › Mass spectrometry LC-MS high-resolution MS mass error (ppm) Pinned Wiki LC-MS and high-resolution MS, charge states, mass accuracy in ppm, and what identity confirmation does and does not establish. This post is a community wiki: any member at trust level 3 or above can edit it,…	+5	9	19k	6h
Coming back to: Pricing far outside the range, in either direction Sourcing › Red flags documentation quality underdosing mislabelling Pricing far outside the range, in either direction Writing it up because I had to work it out twice and would rather nobody else did. Pricing far outside the range — I have the observation and I do not trust…	+22	26	325	2y
Coming back to: Batch date after test date, and other internal inconsistencies Analytics › COA interpretation reference standards amino acid analysis documentation quality certificate of analysis On the subject in the title: Batch date after test date, and other internal inconsistencies Working notes rather than a conclusion. Batch date — I have the observation and I do not trust my interpretation of…	+21	27	420	3h
Interpreting a composition change that is within the error bars Outcomes › Body composition bioimpedance data table lean mass loss On the subject in the title: Interpreting a composition change that is within the error bars Working notes rather than a conclusion. Asking about interpreting a composition change directly, because I have…	+18	22	5.8k	12mo
HbA1c lag and what it can and cannot tell you at eight weeks — one year on Clinical › Bloodwork liver enzymes lipase & amylase lipid panel thyroid function Posting this under the heading it deserves: HbA1c lag and what it can and cannot tell you at eight weeks — one year on Everything below is what sits behind that. A methods question rather than a substantive…	+18	22	655	13h
Semaglutide and alcohol: what is actually documented Compounds › Semaglutide STEP programme randomised trial type 2 diabetes SELECT trial Posting this under the heading it deserves: Semaglutide and alcohol: what is actually documented Everything below is what sits behind that. I would like to know what people here actually do about semaglutide…	+14	18	10k	2d
Books and papers worth reading that are not about this at all Lounge › Off topic beginner friendly long read On the subject in the title: Books and papers worth reading that are not about this at all Working notes rather than a conclusion. Reading back through what has been written here about books and papers, three…	+13	17	13k	19mo
Ipamorelin selectivity claims and where they came from — a second dataset Compounds › Secretagogues & GH axis CJC-1295 GHRP class tesamorelin ipamorelin Posting this under the heading it deserves: Ipamorelin selectivity claims and where they came from — a second dataset Everything below is what sits behind that. Posting a small dataset on Ipamorelin…		2	27k	14mo
What a simple presence test is genuinely useful for — does this still hold? Analytics › Home & field testing ELISA LOD & LOQ third-party testing documentation quality Solved Pinned What a simple presence test is genuinely useful for — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Trying to work out what would count as…		2	22k	16mo
A well-designed study with a badly written abstract — does this still hold? Evidence › Study critique disputed confounding risk of bias Solved Closed A well-designed study with a badly written abstract — does this still hold? I have a specific reason for asking rather than idle curiosity, and the context is below. Asking about well-designed study on behalf…		2	28k	20mo
Tracking semaglutide's approved indications across jurisdictions, dated Compounds › Semaglutide semaglutide effect size SELECT trial Tracking semaglutide's approved indications across jurisdictions, dated Writing it up because I had to work it out twice and would rather nobody else did. Putting the numbers in the first post, because a…	+15	19	2.8k	1d
Amylin receptor signalling and satiety Pharmacology › Receptor biology tirzepatide semaglutide amylin analogues Wiki Amylin receptor signalling and satiety Writing it up because I had to work it out twice and would rather nobody else did. Asking about amylin receptor signalling and satiety directly, because I have read four…	+22	26	1.8k	9mo
Isotope patterns and why the monoisotopic peak is not the tallest Analytics › Mass spectrometry LC-MS MALDI-TOF mass error (ppm) high-resolution MS Isotope patterns and why the monoisotopic peak is not the tallest — setting out what I have, and where I think it stops being reliable. Isotope patterns: what I expected, what I found, and the gap between…	+12	16	7.5k	17mo
Coming back to: Request: tag synonyms surfaced in search Meta › Feature requests site feedback wiki post translation Solved Request: tag synonyms surfaced in search Writing it up because I had to work it out twice and would rather nobody else did. Tag synonyms surfaced in search — I have the observation and I do not trust my…		2	26k	13mo
Coming back to: Where the integrator drew the baseline, and how much it moved the number Analytics › HPLC & UHPLC peak integration gradient method UV & DAD detection data table On the subject in the title: Where the integrator drew the baseline, and how much it moved the number Working notes rather than a conclusion. Posting the method first, because I know what the first three…	+20	24	2.7k	10mo
When a tidy document is a signal and when it is decoration Analytics › COA interpretation certificate of analysis reference standards batch & lot numbers amino acid analysis When a tidy document is a signal and when it is decoration I have a specific reason for asking rather than idle curiosity, and the context is below. What changes if the standard account of tidy document is…	+6	10	20k	10mo
Second pass at: A reconstituted vial's beyond-use date and the reasoning behind common figures Practice › Storage & stability beyond-use date cold chain temperature excursion freeze-thaw Solved Second pass at: A reconstituted vial's beyond-use date and the reasoning behind common figures Writing it up because I had to work it out twice and would rather nobody else did. Something changed and I would…	+4	8	20k	8mo
About the Feature requests category Meta › Feature requests site feedback wiki post translation Pinned Wiki Closed Requests for platform and documentation features, with the reasoning that justifies them. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its…		4	28k	9mo
When a network meta-analysis is defensible and when it is not Evidence › Meta-analyses effect size heterogeneity publication bias Solved When a network meta-analysis is defensible and when it is not I have a specific reason for asking rather than idle curiosity, and the context is below. Network meta-analysis, from the point of view of someone…		2	27k	4h
Why the Start Here categories exist, and what they are not for — one year on Start Here › Welcome onboarding beginner friendly guidelines Solved Why the Start Here categories exist, and what they are not for — one year on I have a specific reason for asking rather than idle curiosity, and the context is below. Collecting what is known about Start in…	+11	15	566	18mo
Why the cheapest option is often not the cheapest Access › Pricing compounding formulary cost per milligram data table Solved Wiki Why the cheapest option is often not the cheapest I have a specific reason for asking rather than idle curiosity, and the context is below. Cheapest option: setting out the arithmetic in full, because I have…	+19	23	1.2k	12h
Language barriers in accessing a prescription abroad Access › International personal import telehealth EMA Solved Language barriers in accessing a prescription abroad Writing it up because I had to work it out twice and would rather nobody else did. I was wrong about language barriers in accessing in a thread last spring…		2	22k	1h
About the European Union category Regional › European Union EMA personal import cost per milligram Pinned Wiki Closed EMA positions, national differences within the EU, and cross-border purchase rules. This post is a community wiki: any member at trust level 3 or above can edit it, and every edit is recorded with its author…	+1	5	18k	10mo